ORGANIC CHEMISTS FOCUSED ON BIOMOLECULE SYNTHESIS

PUBLICATIONS

2026

108.​ Activation of Pro-survival Autophagy by a Small Molecule Promoting p62 Oligomerisation

J. Panek, E. Fielder, C. Sun, S. Crabtree, T. Kataura, N. Wilson, L. Baheerathan, J. Tang, L., W. Yue, G. Richardson, L. Holder, G. J. Miller, J. Reynisson, S. Sarkar and V. I. Korolchuk, J. Biol. Chem., 2026, 302, 113430.

107.​ A Glycosaminoglycan-Binding LecA-Like Lectin from Xenorhabdus nematophila: Structural and Biophysical Characterization

M. Korsák, J. Komárek, J. Houser, I. Pongener, G. J. Miller and M. Wimmerová, Carbohydr. Polym., 2026, 388, 125557.

106.​ Stereocontrolled Synthesis of Rare L-Glycosyl 1-Phosphates for Probing Nucleotidyltransferases

L. N. D. Beardmore, A. Ghosh, A. Koid, G. J. Miller, M. Zheng, T. J. Lupoli and A. Ní Cheallaigh, ChemRxiv, doi:10.26434/chemrxiv.15004674/v1.

105.​ An H-Phosphonate-mediated Synthesis of Nucleotide-Pyranose Glycoconjugates

T. Guillaume, N. Huang, M. Smith and G. J. Miller, Org. Lett., 2026, 28, 7913–7917.

104.​ 3-Deoxy-3-Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

S. T. Evans, N. Yadav, W. A. Remmerswaal, D. Hoogers, K. N. A. van de Vrande, S. Hosking, A. Poveda, J. D. C. Codée, J. Jiménez-Barbero, M. Delbianco and G. J. Miller, Angew. Chem. Int. Ed., 2026, 65, e5914227.

103.​ An Enzyme Cascade for Production of Key RNA Therapeutic Building Blocks Using Simple Phosphate Donors

Q. Meng, C. Benckendorff, C. Morrill, Y. Zhuo, A. Egerström, A. Ní Cheallaigh, S. Derrington, R. Obexer, M. Ortmayer, C. Levy, J. D. Finnigan, S. J. Charnock, N. J. Turner, G. J. Miller and S. L. Lovelock, Nat. Commun., 2026, 17, 626.

102.​ Aspergillus fumigatus PolX1 is an early ancestor of vertebrate terminal deoxynucleotidyl transferases

N. Parveen, S. Steblina, A. Behera, C. M. M. Benckendorff, G. J. Miller, K. E. Davis and P. Mukherjee, Nucleic Acids Res., 2026, 54, gkaf1497.

101.​ Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

Z. Li, H. Chawla, L. Di Vagno, A. Ni Cheallaigh, M. Crichter, D. Sammon, E. Gonzalez-Rodriguez, D. C. Briggs, N. Chung, V. Chang, K. E. Mahoney, A. Cioce, G. Bineva-Todd, P.-Y. Chang, Y.-C. Liu, L. D. Murphy, Y.-H. Chen, Y. Narimatsu, R. L. Miller, L. I. Willems, S. A. Malaker, M. L. Huang, G. J. Miller, E. Hohenester and B. Schumann, Nat. Chem. Biol., 2026, 22, 612-621.

100.​ Enzymatic access to the rare ΔUA (1→4) Glc 3,6-N-sulfated heparin disaccharide, implications for heparin quality control

T. K. Kandola, C. J. Mycroft-West, M. L. Andrade De Lima, A. Turner, C. Gardini, E. Urso, G. J. Miller, A. Bisio, E. A. Yates, M. Guerrini, L. Wu, M. A. Skidmore, BioRxiv, doi: 10.1101/2024.09.26.615151.

99. Exploration of a heparosan trisaccharide synthesis: donor evaluation and characterisation of an unexpected glucuronic acid acceptor pyranose to furanose ring contraction

I. Pongener and G. J. Miller, Carbohydr. Res., 2026, 560, 109788.

Part of a Virtual Special Issue from EUROCARB 2025.

98.​ Lewis Acidic UiO-67 as a Catalyst for the Hydroboration of Aldehydes

P. R. Hawkins, L. N. D. Beardmore, G. J. Miller, S. C. Cosgrove, C. S. Hawes and P. D. Matthews, Eur. J. Inorg. Chem., 2026, e202500626.

2025

97. Adenosine deaminase: structure–activity relationships and harnessing biocatalysis to access purine nucleoside analogues

H. S. Wootton, A. Maganza-Zurdo, Y. S. Sanghvi, S. C. Cosgrove and G. J. Miller, Trends Chem., 2025, 7, 801-815.

Part of a Special Issue: The Chemistry of Nucleic Acids

96.​ A biocatalytic platform for nucleoside monophosphate synthesis in continuous flow

A. Naramittanakul, S Sari, C. M. M. Benckendorff, J. Cheang, Y. S. Sanghvi; G. J. Miller and S. C. Cosgrove, ChemRxiv, doi: 10.26434/chemrxiv-2025-snvjk.

95. Fluorinating the Sugar and the Nucleotide: Exploring Fluorination Within GDP-Mannose Probes Using Chemoenzymatic Synthesis

J. P. Dolan, S. T. Evans, C. M. M. Benckendorff, S. Sari, A. Ní Cheallaigh and G. J. Miller, J. Am. Chem. Soc. Au, 2025, 8, 3994–4001.

94. Advances and Challenges in Bioprocess Optimisation for the Synthesis of Sugar Nucleotides

T. Roberts, S. C. Cosgrove and G. J. Miller, ChemBioChem, 2025, 26, e202500434.

93. Polyvalent Mannuronic Acid-Coated Gold Nanoparticles for Probing Multivalent Lectin–Glycan Interaction and Blocking Virus Infection

R. Basaran, D. Budhadev, E. Dimitriou, H. S. Wootton, G. J. Miller, A. Kempf, I. Nehlmeier, S. Pöhlmann, Y. Guo and D. Zhou, Viruses, 2025, 17, 1066.

Part of a Special Issue: Role of Lectins in Viral Infections and Antiviral Intervention

92. Synthesis of Allyl 2-acetamido-2-deoxy-β-D-galactopyranoside

J. Porter, S. S. Berry, C. S. Haydon and G. J. Miller, Carbohydrate Chemistry: Proven Synthetic Methods, 6, 2025, in production, CRC Press.

91. Synthesis of Orthogonally Protected p-Tolyl 2-azido-3-O-benzyl-6-Otert-butyldiphenylsilyl-2-deoxy-4-O-levulinoyl-1-thio-β-D-glucopyranoside

I. Pongener, D. Hoard and G. J. Miller, Carbohydrate Chemistry: Proven Synthetic Methods, 6, 2025, in production, CRC Press.

90. Systematic Studies Toward the Synthesis of D-Galactosamine-containing Coumarin Glycosides

H. S. Wootton and G. J. Miller, Org. Biomol. Chem., 2025, 23, 5682-5688.

89. Photoinitiated thiol-ene mediated functionalization of 4,5-enoses

A. Prieto-Castañeda, H. Martin, T. Manna, L. Beswick, J. T. McLean, I. Pongener, I. R. González, B. Twamley, G. J. Miller* and E. M. Scanlan,* Org. Biomol. Chem, 2025, 23, 5332-5338.

88. A modular, reusable biocatalytic flow system for UDP-GlcNAc production

T. Roberts, J. P. Dolan, G. J. Miller,* M. A Lima* and S. C. Cosgrove,* React. Chem. Eng., 2025, 10, 1221-1226.

87. 3′-O-β-Glucosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

J. P. Dolan, T. Keenan, A. Ní Cheallaigh, M. A. Fascione and G. J. Miller, RSC Chem. Biol., 2025, 6, 845-850

85. 3,4,6-Tri-O-acetyl-1-S-acetyl-2-deoxy-2-S-phenylthio-α-D-mannopyranoside

J. Porter and G. J. Miller, Molbank, 2025, M1981.

2024

83. Synthesis of Nucleoside Analogues Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon 

C. M. M. Benckendorff, P. Sunde-Brown, A. Ní Cheallaigh and G. J. Miller, J. Org. Chem., 2024, 89, 16977–16989.

82. Sugar-coated: can multivalent glycoconjugates improve upon nature’s design?

K. G. Leslie, S. S. Berry, G. J. Miller* and C. S. Mahon* J. Am. Chem. Soc., 2024, 146, 27215–27232.

80. Benzoylation of tetrols: a comparison of regioselectivity patterns for O– and S-glycosides of D-galactose

J. Porter, J. Roberts and G. J. Miller, J. Org. Chem., 2024, 89, 14090–14097​.

79. Adaptable Synthesis of Chondroitin Sulfate Disaccharide Subtypes Preprogrammed for Regiospecific O-Sulfation

H. S. Wootton, S. S. Berry, E. L. Ferguson, C. S. Mahon and G. J. Miller Eur. J. Org. Chem., 2024, 27, e202400587.

78. Tandem One-Pot Biocatalytic Oxidation and Wittig Reaction in Water

A. J. C. Wahart, L. N. D. Beardmore, R. A. Field, S. C. Cosgrove* and G. J. Miller* Org. Lett., 2024, 26, 6642–6646.

77. Methyl and Benzyl (ethyl 3,4-di-O-benzyl-2-O-benzoyl-1-thio-β-D-glucopyranosyl)uronate​

H. S. Wootton and G. J. Miller, Molbank, 2024, 3, M1847.

76. Exploring a Gemcitabine-Glucose Hybrid as a Glycoconjugate Prodrug

J. Porter, A. R. Noble, N. Signoret, M. A. Fascione, and G. J. Miller, ACS Omega, 2024, 9,  31703–31713.

75.​ Biocatalytic Nucleobase Diversification of 4′-Thionucleosides and Application of Derived 5-Ethynyl-4′-thiouridine for RNA synthesis detection

S. Westarp, C. Benckendorff, J. Motter, V. Röhrs, Y. Sanghvi, P. Neubauer, J. Kurreck, A. Kurreck and G. J. Miller, Angew. Chem. Int. Ed., 2024, 63, e202405040​.

74. Synthesis of a Heparan Sulfate Tetrasaccharide using Automated Glycan Assembly 

I. Pongener, E. T. Sletten, J. Danglad-Flores, P. H. Seeberger and G. J. Miller, Org. Biomol. Chem., 2024, 22, 1395-1399.

73. Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology

J. Motter, C. M. M. Benckendorff, S. Westarp, P. Sunde-Brown, P. Neubauer, A. Kurreck* and G. J. Miller*, Nat. Prod. Rep., 2024, 41, 873-884.

Featured on the Front Cover of the Issue

72. Chemical diversification of carbocyclic fluorinated pyrimidine nucleosides: introducing 2’-arabino analogues and ring unsaturation​

C. M. M. Benckendorff, C. S. Hawes, M. Smith and G. J. Miller, Synlett., 2024, 35, 659-664.

Part of a Special Issue to Celebrate the Centenary Year of Prof. Har Gobind Khorana

71. Harnessing a biocatalyst to bioremediate the purification of alkylglycosides

A. J. C. Wahart, J. P. Dolan; S. D. Anderson, A. Ní Cheallaigh, J. Staniland, M. A. Lima; M. A. Skidmore, G. J. Miller* and S. Cosgrove*, ChemBioChem., 2024, 25, e202300625.

Cover Feature 

2023

70. Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library​

T. Keenan, N. Hatton, J. Porter, J.-P. Vendeville, D. Wheatley, M. Ghirardello, A. J. C. Wahart, S. Ahmadipour, J. Walton, C. Galan, B. Linclau, G. J. Miller* and M. A. Fascione*, Chem. Sci., 2023, 14, 11638-11646.

Featured as Back Cover.

69. A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

J. M. Hoolachan, E. McCallion, E. R. Sutton, Ö. Çetin, P. Pacheco-Torres, M. Dimitriadi, S. Sari, G. J Miller, M. Okoh, L. M. Walter, P. Claus, M. J. A. Wood, D. P. Tonge and M. Bowerman, Hum. Mol. Genet., 2023, ddad192​.

68. Preparation of a 4′-thiouridine building-block for solid-phase oligonucleotide synthesis

C. M. M. Benckendorff, Y. S. Sanghvi and G. J. Miller, Current Protocols in Nucleic Acid Chemistry, 2023, 3, e878.

67. Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors

J. P. Dolan, S. Ahmadipour, A. J. C. Wahart, S. Sari, A. Ní Cheallaigh, C. Eurtivong, M. A. Lima, M. A. Skidmore, K. Volcho, J. Reynisson, R. Field and G. J. Miller, RSC Chem. Biol., 2023, 4, 865-870.

Part of a themed collection: Medicinal Chemistry Small Molecule Probes

Correction: RSC Chem. Biol., 2024, 5, 800-801.

66. Indolo[2,3-e]benzazocines and indolo[2,3-f]benzazonines and their copper(II) complexes as microtubule destabilizing agents

C. Wittmann, O. Dömötör, I. Kuznetcova, G. Spengler, J. Reynisson, L. Holder, G. J. Miller, E. A. Enyedy, R. Bai, E. Hamele and V. B. Arion, Dalton Trans., 2023, 52, 9964-9982.

65. Fluorinated Nucleosides, Nucleotides & Sugar-Nucleotides 

J. P. Dolan,* C. M. M. Benckendorff,* R. A. Field and G. J. Miller, Fut. Med. Chem., 2023, 15, 1111-1114.

63. Realizing the continuous chemoenzymatic synthesis of anilines using an immobilized nitroreductase

S. C. Cosgrove, G. J. Miller, A. Bornadel and B. Dominguez, ACS Sust. Chem. Eng., 2023, 11, 8556-8561

62. Chemical synthesis of amphiphilic glycoconjugates: Access to amino, fluorinated and sulfhydryl oleyl glucosides

J. Porter, D. Parisi, T. Miller, A. Ní Cheallaigh and G. J. Miller Carbohydr. Res., 2023, 530, 108854.

61. Early Career Researchers in Glycoscience

G. J. Miller Carbohydr. Res., 2023, 108763.

60. A sulphated glycosaminoglycan extract from Placopecten magellanicus inhibits the Alzheimer’s disease β-Site amyloid precursor protein cleaving enzyme 1 (BACE-1)

C. J. Mycroft-West, A. J. Devlin, L. C. Cooper, S. E. Guimond, P. Procter, G. J. Miller, M. Guerrini, D. G. Fernig, E. A. Yates, M. A. Lima and M. A. Skidmore Carbohydr. Res., 2023, 108747.

59. Synthesis of 4-thio-D-glucopyranose and interconversion to 4-thio-D-glucofuranose

J. Porter, M. A. Lima, I. Pongener and G. J. Miller Carbohydr. Res., 2023, 108759.

58. Synthesis of a B-Antigen Hexasaccharide, a B-Lewis b Heptasaccharide and Glycoconjugates Thereof to Investigate Binding Properties of Helicobacter pylori

M Reihill, V. Fournière, A. Ní Cheallaigh, J. Olofsson, G. J. Miller, T. Borén, M. Lahmann and S. Oscarson Chem. Eur J., 2023, e202203672.

57. Biocatalytic Approaches to Building Blocks for Enzymatic and Chemical Glycan Synthesis

J. P. Dolan, S. C. Cosgrove and G. J. Miller, JACSAu2023, 3, 47-61.

2022

56. Synthetic FRET enabled carbohydrate active enzyme probes

M. Singh, M. Watkinson, E. M. Scanlan and G. J. Miller, 2022, Davey G.P. (eds) Glycosylation. Methods in Molecular Biology, vol 2370. Humana, New York, NY, 237-264.

55. Synthesis of fluorinated carbocyclic pyrimidine nucleoside analogues

C. M. M. Benckendorff, V. D. Slyusarchuk, N. Huang, M. A. Lima, M. Smith and G. J. Miller, Org. Biomol. Chem.2022, 20, 9469-9489.

54. Synthesis of C6-modified mannose 1-phosphates and evaluation of derived sugar nucleotides against GDP-mannose dehydrogenase

S. Ahmadipour, A. J. C. Wahart, J. P. Dolan,  L. Beswick, C. S. Hawes, R. A. Field and G. J. Miller, Beilstein J. Org. Chem., 2022, 18, 1379-1384.

53. Using NMR to Dissect the Chemical Space and O-Sulfation Effects within the O– and S-Glycoside Analogues of Heparan Sulfate

M. C. Z. Meneghetti, L. Naughton, C. O’Shea, D. S.-E. Koffi Teki, V. Chagnault, H. B. Nader, T. R. Rudd, E. A. Yates, J. Kovensky, G. J. Miller and M. A. Lima, ACS Omega, 2022, 7, 24461-24467.

52. Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues

S. C. Cosgrove and G. J. Miller, Expert Opin. Drug Discovery, 2022, 17, 355-364.

51. Design, chemical synthesis and antiviral evaluation of 2’-deoxy-2’-fluoro-2’-C-methyl-4’-thionucleosides​

M. Guinan, N. Huang, M. Smith and G. J. Miller, Bioorg. Med. Chem. Lett., 2022, 61, 128605.

50. Oxidase enzymes as sustainable oxidation catalysts

A. Wahart, J. Stanisland, G. J. Miller and S. C. Cosgrove, R. Soc. Open Sci., 2022, 9, 211572.

49. Sweet targets: sugar nucleotide biosynthesis inhibitors

S. Ahmadipour, J. Reynisson, R. A. Field and G. J. Miller, Fut. Med. Chem., 2022, 14, 295-298.

48. Chemical synthesis of 4’-thio and 4’-sulfinyl pyrimidine nucleoside analogues

M. Guinan, N. Huang, C. S. Hawes, M. Lima, M. Smith and G. J. Miller, Org. Biomol. Chem., 2022, 20, 1401-1406.

Front Cover and part of a themed collection – Chemical Biology in OBC

2021

47. Prospects for anti-Candida therapy through targeting the cell wall: a mini-review

S. Ahmadipour, R. A. Field and G. J. Miller, Cell. Surf., 2021, 7, 100063.

46. Developments in the Chemical Synthesis of Heparin and Heparan Sulfate

I. Pongener, C. O’Shea, H. Wootton, M. Watkinson and G. J. Miller, Chem. Rec., 2021, 21, 1-19

Part of a Special Issue – Recent Advances in Carbohydrate Chemistry

45. Chemical synthesis of C6-tetrazole D-mannose building blocks and access to a bioisostere of mannuronic acid 1-phosphate

E. Dimitriou and G. J. Miller, Beilstein J. Org. Chem. 2021, 17, 1527–1532

44. Glycosaminoglycans from Litopenaeus vannamei inhibit the Alzheimer’s disease β-secretase, BACE1

C. J. Mycroft-West, A. J. Devlin, L. C. Cooper, S. E. Guimond, P. Procter, G. J. Miller, M. Guerrini, D. G. Fernig, E. A. Yates, M. A. Lima and M. A. Skidmore, Marine Drugs, 2021, 19, 203.

Part of a special issue – Anti-Alzheimer Agents from Marine Sources

2020

43. Synthesis of 1’-(4’-thio-β-D-ribofuranosyl) uracil

M. Guinan, D. Lynch, M. Smith and G. J. Miller, Carbohydrate Chemistry: Proven Synthetic Methods, 5, ch. 28, 2020, 237-232, CRC Press.

42. Synthesis of dibenzyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl phosphate

S Ahmadipour, B. Riedl and G. J. Miller, Carbohydrate Chemistry: Proven Synthetic Methods, 5, ch.17, 2020, 135-140, CRC Press.

41. Targeted chemoenzymatic synthesis of sugar nucleotide probes reveal an inhibitor of the GDP-D-mannose dehydrogenase from Pseudomonas aeruginosa

L. Beswick, E. Dimitriou, S. Ahmadipour, A. Zafar, M. Rejzek, J. Reynisson, R. A. Field and G. J. Miller, ACS Chem Biol., 2020, 15, 3086-92.

40. Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin

C. J. Mycroft-West, D. Su, I. Pagani, T. Rudd, S. Elli, N. Gandhi, S. Guimond, G. J. Miller, M, Meneghetti, H. Nader, Y. Li, Q. M. Nunes, P. Procter, N. Mancini,  M. Clementi, A. Bisio, N. R. Forsyth, V. Ferro, J. E. Turnbull, M. Guerrini, D. G. Fernig, E. Vicenzi, E. A. Yates, M. A. Lima, M. A. Skidmore Thromb. Haemost., 2020, 120, 1700–1715.

39. Illuminating glycoscience: Synthetic strategies for FRET-enabled carbohydrate active enzyme probes

M. Singh, M. Watkinson, E. M. Scanlan and G. J. Miller, RSC Chem. Biol., 2020, 1, 352-68.

38. Unifying the synthesis of nucleoside analogs

G. J. Miller, Science, 2020, 369, 623.

37. Chemical synthesis of a sulfated D-glucosamine library and evaluation of cell proliferation capabilities

A. Ní Cheallaigh, S. E.Guimond, S. Oscarson and G. J. Miller, Carbohydr. Res., 2020, 495, 108085.

36. Recent advances in the chemical synthesis and evaluation of anticancer nucleoside analogues

M. Guinan, C. Benckendorff, M. Smith and G. J. Miller, Molecules, 2020, 25, 2050.

Part of a Special Issue – Advances in Anticancer Drug Discovery

34. Exploring anomeric glycosylation of phosphoric acid: optimisation and scope for non-native substrates

L. Beswick, S. Ahmadipour, G.-J. Hofman, H. Wootton, E. Dimitriou, J. Reynisson, R. A. Field, B. Linclau and G. J. Miller. Carbohydr. Res., 2020, 488, 107896.

33. Inhibition of BACE1, the β-secretase implicated in Alzheimer’s Disease, by a chondroitin sulfate extract from Sardina pilchardus

C. J. Mycroft-West, A. J. Devlin, C. L. Cooper, P. Procter, G. J. Miller, D. G. Fernig, M. Guerrini, S. E. Guimond, M. A. de Lima, E. A. Yates and M. Skidmore, Neur. Regen. Res., 2020, 15, 1546-1553.

Pre 2020

32. Exploring a glycosylation methodology for the synthesis of hydroxamate-modified alginate building blocks

E. Dimitriou and G. J. Miller, Org. Biomol. Chem, 2019, 17, 9321-9335.

Part of a Web-Themed Special Issue – Glycosylation: New methodologies and applications

31. Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP mannuronic acid

L. Beswick, S. Ahmadipour, J. P. Dolan, M. Rejzek, R. A. Field and G. J. Miller, Carbohydr. Res., 2019, 485, 107819.

30. 6R/S-deutero-α-D-mannopyranoside 1-phosphate

S. Ahmadipour and G. J. Miller, Molbank, 2019, 2019, M1068.

Part of a Special Issue – Organic Synthesis of Carbohydrates

29. Chemoenzymatic synthesis of C6-modified sugar-nucleotides to probe the GDP mannose dehydrogenase from Pseudomonas aeruginosa

S. Ahmadipour, G. Pergolizzi, M. Rejzek, R. A. Field and G. J. Miller, Org. Lett., 2019, 21, 4415-4419.

28. Gas-liquid flow hydrogenation of nitroarenes: efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold

E. Dimitriou, R. H. Jones, R. G. Pritchard, G. J. Miller* and M. O’Brien*, Tetrahedron, 2018, 74, 6795-6803.

27. Recent advances in the enzymatic synthesis of sugar-nucleotides using nucleotidylyltransferases and glycosyltransferases

S. Ahmadipour, L. Beswick and G. J. Miller, Carbohydr. Res., 2018, 469, 38-47.

26. Synthesis of 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose using the diazo-transfer reagent imidazole-1-sulfonyl azide hydrogen sulfate

G. T. Potter, G. C. Jayson, J. M. Gardiner, L. Guazelli and G. J. Miller, J. Carb. Chem., 2018, 37, 178.

25. Synthesis of 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose using the diazo-transfer reagent imidazole-1-sulfonyl azide hydrogen sulfate

G. T. Potter, L. Guazelli, G. C. Jayson, G. J. Miller, J. M. Gardiner, Carbohydrate Chemistry: Proven Synthetic Methods, 4, ch.18, 2017, 151-156, CRC Press.

24. Recent advances in the chemical synthesis of sugar-nucleotides

S. Ahmadipour and G. J. Miller, Carbohydr. Res., 2017, 451, 95-109.

Part of a virtual special issue – Eurocarb 2017.

23. 1,2,3,4-Tetra-O-Acetyl-D-mannuronic acid

L. Beswick and G. J. Miller, Molbank, 2017, 2017, M947.

22. Synthetic Site-Selectively Mono-6-O-Sulfated Heparan Sulfate Dodecasaccharide Shows Anti-Angiogenic Properties In Vitro and Sensitizes Tumors to Cisplatin In Vivo

E. Avizienyte, C. L. Cole, G. Rushton, G. J. Miller, A. Bugatti, M. Presta, J. M. Gardiner and G. C. Jayson, PLoS ONE, 2016, 11, e0159739.

21. Preparation of Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronate

A. Ní Cheallaigh, G. T. Potter, J. M. Gardiner and G. J. Miller, Org. Synth., 2016, 93, 200-209.

20. An Updated Synthesis of the Diazo-Transfer Reagent Imidazole-1-sulfonyl Azide Hydrogen Sulfate

G. T. Potter, G. C. Jayson, G. J. Miller and J. M. Gardiner, J. Org. Chem., 2016, 81, 3443–3446.

19. Amyl nitrite-mediated conversion of aromatic and heteroaromatic primary amides to carboxylic acids

G. T. Potter, G. C. Jayson, G. J. Miller, J. M. Gardiner, Tetrahedron Lett., 2015, 56, 5153-5156.

18. Modular Synthesis of Heparin-Related Tetra-, Hexa- and Octasaccharides with Differential O-6 Protections: Programming for Regiodefined 6-O-Modifications

M. Barath, S. U. Hansen, C. E. Dalton, G. C. Jayson, G. J. Miller, J. M. Gardiner, Molecules, 2015, 20, 6167-6180.

Part of a Special Issue – Glycosaminoglycans and their Mimetics.

16. A latent reactive handle for functionalising heparin-like and LMWH deca- and dodecasaccharides

G. J. Miller, K. R. Broberg, C. Rudd, M. R. Helliwell, G. C. Jayson, J. M. Gardiner, Org. Biomol. Chem., 2015, 13, 11208-11219.

15. Making the longest sugars: a chemical synthesis of heparin-related [4]n oligosaccharides from 16-mer to 40-mer

S. U. Hansen*, G. J. Miller*, M. J. Cliff, G. C. Jayson, J. M. Gardiner, Chem. Sci., 2015, 6, 6158-6164.

Referee recommended Hot Article, July 2015.

14. Development of synthetic heparan sulfate oligosaccharides as anti-angiogenic agents

G. C. Jayson, S. U. Hansen, G. J. Miller, C. L. Cole, G. Rushton, J. M. Gardiner, E. Avizienyte, Cancer Res., 2015, 75, 1375.

13. Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology

G. C. Jayson, S. U. Hansen, G. J. Miller, C. L. Cole, G. Rushton, E. Avizienyte, J. M. Gardiner, Chem. Commun., 2015, 51, 13836-13849.

12. The development of anti-angiogenic heparan sulfate oligosaccharides

G. C. Jayson, G. J. Miller, S. U. Hansen, M. Baráth, J. M .Gardiner, E. Avizienyte, Biochem. Soc. Trans., 2014, 42, 1596-1600.

11. Synthesis of a heparin-related GlcN–IdoA sulfation-site variable disaccharide library and analysis by Raman and ROA spectroscopy

G. J. Miller, S. U. Hansen, M. Baráth, C. Johannessen, E. Blanch, G. C. Jayson, J. M .Gardiner, Carbohydr. Res., 2014, 400, 44-53.

10. Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion

N. Takemoto, T. Suehara, H. Frisco, S.-I. Sato, T. Sezaki, K. Kusamori, Y. Kawazoe, S. M. Park, S. Yamazoe, Y. Mizuhata, R. Inoue, G. J. Miller, S. U. Hansen, G. C. Jayson, J. M. Gardiner, T. Kanaya, N. Tokitoh, K. Ueda, Y. Takakura, N. Kioka, M. Nishikawa, M. Uesugi, J. Am. Chem. Soc., 2013, 135, 11032-11039.

9. Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies

S. U. Hansen*, G. J. Miller*, G. Rushton, E. Avizienyte, C. Cole, G. C. Jayson, J. M. Gardiner, Nature Commun., 2013, 4, 2016.

8. Efficient chemical synthesis of heparin-like octa-, deca- and dodecasaccharides and inhibition of FGF2- and VEGF165-mediated endothelial cell functions

G. J. Miller, S. U. Hansen, M. Baráth, G. Rushton, C. Cole, E. Avizienyte, G. C. Jayson, J. M. Gardiner, Chem. Sci., 2013, 4, 3218-3222.

7. First Gram-Scale Synthesis of a Heparin-Related Dodecasaccharide

S. U. Hansen, G. J. Miller, G. C. Jayson, J. M. Gardiner, Org. Lett., 2013, 15, 88-91.

C&EN News Highlight Article

6. Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

D. C. Pryde, L. H. Jones, D. P. Gervais, D. R. Stead, D. C. Blakemore, M. D. Selby, A. D. Brown, J. W. Coe, M. Badland, D. M. Beal, R. Glen, Y. Wharton, G. J. Miller, P. White, N. Zhang, M. Benoit, K. Robertson, J. R. Merson, H. L. Davis, M. J. McCluskie, PLoS ONE, 2013, 10, e76557.

5. Synthesis and Scalable Conversion of L-Iduronamides to Heparin- Related Di- and Tetrasaccharides

S. U. Hansen*, G. J. Miller*, M. Baráth, K. R. Broberg, E. Avizienyte, G. C. Jayson, J. M. Gardiner, J. Org. Chem., 2012, 77, 7823-7843.

4. A synthesis of C-glycosidic multivalent mannosides suitable for divergent functionalized conjugation

G. J. Miller, J. M. Gardiner, Tetrahedr. Lett., 2011, 52, 3216–3218.

3. Adaptable Synthesis of C-Glycosidic Multivalent Carbohydrates and Succinamide-Linked Derivatization

G. J. Miller, J. M. Gardiner, Org. Lett., 2010, 12, 5262-5265.

2. Synthesis of the Marine Glycolipid Dioctadecanoyl Discoside

G. J. Florence, T. Aslam, G. J. Miller, G. D. Milne, S. J. Conway, Synlett., 2009, 19, 3099-3102.

1. Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives

S. J. Conway, G. J. Miller, Nat. Prod. Rep., 2007, 24, 687-707.